
Karl Strohmeier
Director, Business Development
Adare Pharma Solutions
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I would like the opportunity to introduce you to Adare Pharma Solution's Stratµm™ injectable drug delivery technology capable of developing both long acting and delayed release formulations.
Stratµm technology creates uniform monodispersed microspheres for improved injectable depot formulations. Stratµm depot formulations for small molecules and proteins allow for discrete control over release rate, including linear kinetics, offering sustained release for weeks, months or years. Stratµm’s uniform particles provide release accuracy for narrow therapeutic index drugs and minimize the initial drug burst for increased safety and efficacy. This application is particularly useful for pharmaceuticals for which compliance is critical, such as contraception, antipsychotic, addiction and bacterial resistance medications.
Stratµm technology also revolutionizes injectable pharmaceuticals with delayed release of active pharmaceutical ingredients for true pulse release. A uniform shell contains high loadings of stabilized active ingredients within the aqueous core. The composition of the shell can be tuned to release the active after a targeted period of time. This technology minimizes the number of injections needed by combining a variety of delayed-release microspheres while also enhancing dosage control through uniform, monodisperse microspheres. Such an approach is particularly useful to improve patient compliance by reducing the number of injections (e.g., vaccines or ocular therapies).
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