Congruence Medical Solutions - Start-Up Pitch

We intend to highlight at CPHI Barcelona our High Dose Autoinjector with Injection Pause.One of the most critical unmet, unsolved needs in injectable drug delivery is to be able to deliver high dose biologics, which tend to be higher in viscosity and larger in injection volume. Autoinjectors have widely been used for self-administration. However, conventional autoinjectors powered by compression springs are unable to provide the injection force necessary to administer viscous, high dose biologics quickly. This results in either long injection times (30 -60+ seconds) where the patient has to press the autoinjector against the skin for the duration of the injection. In some cases, the insufficient force provided by compression springs results in the injection stalling resulting in a lost dose.The Congruence High Dose Autoinjector incorporates a proprietary compressed gas source to provide the force necessary to deliver a viscous, high dose biologic. We have demonstrated ability to inject a 2mL of a 100cP formulation using a standard glass prefilled syringe with a 27G staked needle. This Congruence autoinjector is compact with size similar to a conventional autoinjector (compression spring) designed to inject 1mL of low viscosity (1-5cP) drug.