Precision Drug Delivery: Innovation in High-Dose, Large-Volume Applications
Information
Today’s medicine and therapeutics encompass fairly complex formulations. The device design needs to not only incorporate the challenging needs of the formulation but also address patient optimized administration and deliver consistent results.
The success of the clinical outcome is dependent on the delivery optimization in these situations and thus the importance of methodologies to be able to monitor delivery and evaluate Pharmacokinetics (PK) modeling. The presentation will highlight novel methodologies developed to explore drug characterization, drug delivery optimization, and autoinjector simulator to assess pharmacokinetics / pharmacodynamics towards early evaluation and consistent results. The methodology can be used for novel therapies and unmet needs in various indications including the areas of high dose, large volume and high viscosity applications. Some case studies will be highlighted with the methodology. Topics include aspects of:
- Development process for Drug Delivery
- Delivery Evaluation – Drug, Site, PK-PD modeling
- Path to Device – Injection Parameters Optimization
- Integrated Development Cycle
