FSH E.P.

BSV Bioscience GmbH provides a wide range of biological pharmaceutical active ingredients which includes FSH E.P. It is a glycoprotein hormone secreted by the gonadotrophs in the anterior pituitary gland. The major function of FSH is to promote and sustain the ovarian follicular growth in female and spermatogenesis in male. Structure: it is a member of the glycoprotein hormone family which also includes LH, human chorionic gonadotrophin (HCG) and the thyroid stimulating hormone (TSH). These hormones are heterodimeric proteins comprising a common ?-subunit and a unique ?-subunit which confers the biological specificity to each hormone. FSH has a molecular weight of 32 kDa. Therapeutic indication: it is indicated in hypogonadotrophic hypopituitarism (WHO group I patients) where both gonadotropin stimulations are needed. In patients showing normal or high LH levels (WHO group II patients), require preparations without LH activity, this character belongs to FSH. It is given in a sequential manner are indicated for induction of ovulation in patients with polycystic ovarian disease (PCOD) who have evaluated LH/FSH ratio and who have failed to respond to adequate clomiphene citrate therapy.