Drug Substance

Our streamlined approach to developing drug substance has been shown to reduce manufacturing costs by 50% from preclinical to Phase I. To best support our customer's needs, we have made significant investments in technologies and equipment to meet the increasing demand for complex small-scale drug substance manufacture. With more than 40 years of experience in synthetic organic chemistry coupled with extensive expertise in flow chemistry, synthetic biology and biocatalysis, we can optimize manufacturing processes and save months of development time for our customers. - Process Research and Development- Solid State Services - Capabilities include: - Salt Selection: - Polymorph Screening- Amorphous Dispersions- Crystallization Development - Solid State Characterization: - X-Ray powder diffraction (XRPD) - Theral Analysis (DSC, TGA) - Hygroscopy (DVS)Hot stage microscopy - Particle size distribution and particle enumeration - Surface Area - Solution and Solid State NMRFT-IR - Dissolution/disintegration